Indications

160 mg capsule: An advanced blend of minerals & herbs that can help a proactive approach to prostate health. Uripam supports normal prostate function and healthy urinary flow. It contains Zinc which is required for normal reproductive function.

500 mg capsule: This is indicated in urination problems in benign prostatic hyperplasia stages I & II.

* রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'

Composition

Each 160 mg capsule contains-

• Saw Palmetto Oil 160 mg
• Pygeum Bark Oil 1.7 mg
• Korean Ginseng 3.3 mg
• Zinc Sulphate Monohydrate 33.1 mg
• Copper Gluconate 2 mg

Each 500 mg capsule contains-

• Saw palmetto (Serenoa repens) fruit 500 mg.

Pharmacology

160 mg capsule: Saw Palmetto exerts anti-estrogenic activity, increases urinary fow rate; decreases residual urine; decreases painful urination; decreases nocturia; anti-infammatory activities by following possible mechanisms:

• Inhibits action of 5α-reductase, which catalyzes the metabolism of testosterone to DHT, due to the free fatty acid content of the fruit’s lipophilic extracts.
• Inhibits receptor binding of androgens.
• Inhibits noncompetitively human α 1-adrenoreceptors.
• Inhibits both the cyclooxygenase and lipoxygenase pathways in vitro
• Inhibits growth factors in vitro
• Binds selectively to and increases apoptotic index for prostate cells.

500 mg capsule: Saw palmetto (Serenoa repens) fruit is most commonly used to treat problems related to Benign Prostatic Hyperplasia (BPH). Multiple mechanisms of action have been proposed and Saw palmetto appears to possess 5-alpha reductase inhibitory activity (thereby preventing the conversion of testosterone to dihydrotestosterone). Estrogenic effects as well as direct inhibitory effects on androgen receptors and antiinflammatory properties have also been reported.

Dosage & Administration

160 mg capsule: For Adult use only. The usual dosage is 1-2 capsules daily or as advised by the physician. The safety and effectiveness of Saw Palmetto in the pediatric population have not been established.

500 mg capsule: 1 to 2 g (2-4 capsules) in divided doses daily.

* রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'

Interaction

160 mg capsule: Uripam might decrease the efects of estrogen in the body. Taking Uripam along with birth control pills might decrease the efectiveness of birth control pills.

500 mg capsule: It is believed to exert estrogen, androgen and alpha-adrenergic blocking effects. Because of this, the use of hormones, hormone-like drugs or adrenergic drugs concomitantly may need to be adjusted.

Contraindications

Saw palmetto is not indicated for advanced BPH with severe urinary retention. It should not be used without frst ruling out prostate cancer.

Side Effects

Rare case of GI disturbance has been reported. Ingestion on an empty stomach may cause nausea. Hypertension was reported in 3.1% taking Uripam extract.

Precautions & Warnings

Uripam might slow blood clotting. There is some concern that it might cause extra bleeding during and after surgery. Stop using Uripam at least 2 weeks before a scheduled surgery.

Therapeutic Class

Herbal and Nutraceuticals

Storage Conditions

Store in a cool and dry place, below 30°C. Protect from light & moisture. Keep the medicine out of reach of children.